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Article

Characterization of cell lines stably expressing human normal or mutated EGFP-tagged MC4R.

Journal of biochemistry - 1 Apr 2004

Blondet Antonine, Doghman Mabrouka, Rached Mohamed, Durand Philippe, Bégeot Martine, Naville Danielle

Abstract excerpt

The melanocortin receptor type 4 (MC4-R) is involved in food intake and represents a potential target for the treatment of some forms of obesity. The fluorescent protein EGFP was fused to the wild-type or mutated coding sequence of the human MC4-R. After transfection in HEK 293, clones stably expressing hMC4-R-EGFP were selected. Wild-type chimeric hMC4-R was well addressed to the cell membrane as demonstrated...

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PMID: 15115780
DOI: 10.1093/jb/mvh064

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NDP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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