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Article

Long-range activation of Sox9 in Odd Sex (Ods) mice.

Human molecular genetics - 15 Jun 2004

Qin Yangjun, Kong Ling-kun, Poirier Christophe, Truong Cavatina, Overbeek Paul A, Bishop Colin E

Abstract excerpt

The Odd Sex mouse mutation arose in a transgenic line of mice carrying a tyrosinase minigene driven by the dopachrome tautomerase (Dct) promoter region. The minigene integrated 0.98 Mb upstream of Sox9 and was accompanied by a deletion of 134 kb. This mutation causes female to male sex reversal in XX Ods/+ mice, and a characteristic eye phenotype of microphthalmia with cataracts in all mice carrying the...

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Source

Identifiers

PMID: 15115764
DOI: 10.1093/hmg/ddh141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Long-range activation of Sox9 in Odd Sex (Ods) mice.PMID 15115764Read ↗

A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse.Semantic proximity Read ↗

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Sox9 is sufficient for functional testis development producing fertile male mice in the absence of SrySemantic proximity Read ↗

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Direct interaction of Sox10 with the promoter of murine Dopachrome Tautomerase (Dct) and synergistic activation of Dct expression with Mitf.Semantic proximity Read ↗

The Dark brown plumage color in chickens is caused by an 8.3-kb deletion upstream of SOX10.Semantic proximity Read ↗

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