Article
Deep sequencing of a candidate region harboring the SOX9 gene for the canine XX disorder of sex development.
Animal genetics - 1 Jun 2017
Nowacka-Woszuk J, Szczerbal I, Pausch H, Hundi S, Hytönen M K, Grzemski A, Flisikowski K, Lohi H, Switonski M, Szydlowski M
Abstract excerpt
A disorder of sex development (DSD) in dogs with female sex chromosomes (78, XX), a lack of the SRY gene and the presence of testes or ovotestes is commonly diagnosed in numerous breeds. The molecular background of DSD is not fully recognized but has been linked to the copy number variation in the region harboring the SOX9 gene. We applied a genome-wide association study and targeted next-generation sequencing...
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