Article
BRCA1 and sex ratio.
European journal of human genetics : EJHG - 1 Aug 2004
Struewing Jeffery P, Hartge Patricia, Wacholder Sholom, Tucker Margaret A, Greene Mark H
Abstract excerpt
Two recent papers suggest distorted sex and transmission ratios associated with BRCA1 mutations. If real, these would provide novel insights into the normal biological function of this gene and have implications for genetic epidemiologic methods used to estimate penetrance. We addressed these observations in two settings: offspring of 283 mutation carriers and 471 mutation negative subjects from BRCA1/2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.