Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of BRCA mutations on female fertility and offspring sex ratio.

American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000

Moslehi Roxana, Singh Ranjana, Lessner Lawrence, Friedman Jan M

Abstract excerpt

Positive selection for inherited mutations in breast and ovarian cancer predisposing genes, BRCA1 and BRCA2, may contribute to the high frequency of BRCA mutations among the Ashkenazi Jewish population. Impact of BRCA mutations on fertility has not been generally explored in epidemiologic studies. There are reports of distorted sex ratios in BRCA carrier families but these findings have been attributed to bias....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian Neoplasms
Share to Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Pregnancy

Share to Selection, Genetic

Share to Sex Ratio

Source

Open in PubMed Open full text

Identifiers

PMID: 19642207
DOI: 10.1002/ajhb.20978
PMCID: PMC3739697

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of BRCA mutations on female fertility and offspring sex ratio.PMID 19642207Read ↗

Fertility treatments and breast cancer risk in Jewish Israeli BRCA mutation carriers.Semantic proximity Read ↗

BRCA1 and BRCA2 mutations and female fertility.Semantic proximity Read ↗

Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States).Semantic proximity Read ↗

Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

Fertility treatments and invasive epithelial ovarian cancer risk in Jewish Israeli BRCA1 or BRCA2 mutation carriers.Semantic proximity Read ↗

Hereditary ovarian cancer in Ashkenazi Jews.Semantic proximity Read ↗

Hormone replacement therapy is more prevalent among Jewish BRCA1/2 mutation carriers.Semantic proximity Read ↗

Parity, oral contraceptives, and the risk of ovarian cancer among carriers and noncarriers of a BRCA1 or BRCA2 mutation.Semantic proximity Read ↗

Fertility in women with BRCA mutations: a case-control study.Semantic proximity Read ↗

Effects of BRCA1 and BRCA2 mutations on female fertility.Semantic proximity Read ↗

Effects of BRCA gene mutation on female reproductive potential: A systematic review.Semantic proximity Read ↗

BRCA1 and sex ratio.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.