Article
Association of HLA-DQB1 coding region with unexplained recurrent spontaneous abortion.
Chinese medical journal - 1 Apr 2004
Wang Xi-Peng, Lin Qi-De, Lu Pei-Hua, Ma Zheng-Wen, Zhao Ai-Min
Abstract excerpt
BACKGROUND: DNA analysis has shown a lack of significant compatibility between couples affected by unexplained recurrent spontaneous abortion (URSA) compared with normal fertile couples, [8] although one study that made use of a PCR-sequence-specific oligonucleotide (SSO) method did observe evidence of significant compatibility in the HLA-DQA1 and DQB1 alleles between patients and aborted fetuses. [9] This study...
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