Article
[Association of polymorphisms of HLA-DRB1 gene with unexplained recurrent spontaneous abortion in ethnic Hans from Henan].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2014
He Miao, Kang Bing, Liao Shixiu, Yang Ke, Ding Xuebing, Wu Dong, Guo Qiannan, Hou Qiaofang
Abstract excerpt
OBJECTIVE: To assess the association of polymorphisms of human leukocyte antigen DRB1 gene (HLA-DRB1) with susceptibility to unexplained recurrent spontaneous abortion (URSA). METHODS: The HLA-DRB1 gene was typed with polymerase chain reaction-specific sequence primers (PCR-SSP) method in 200 couples with URSA and 200 couples with a normal pregnancy history. RESULTS: The frequencies of DRB1*09 and DRB1*13 alleles...
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