Article
Detection of mutations in the cDNA of the proliferation marker Ki-67 protein in four tumor cell lines.
Cancer genetics and cytogenetics - 1 Feb 2004
Bubán Tamás, Schmidt Mirko H H, Broll Rainer, Antal-Szalmás Péter, Duchrow Michael
Abstract excerpt
The Ki-67 protein has an essential role in cell proliferation. It is present in all dividing cells of normal and tumor tissues, but absent in resting cells. At present, no data are available about any alterations in the gene of this protein that could contribute to its altered structure and function, resulting in tumor development. We therefore searched for mutations in the Ki-67 gene (MKI67). cDNAs from four...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.