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Article

Impact of methoxymycolic acid production by Mycobacterium bovis BCG vaccines.

Infection and immunity - 1 May 2004

Belley Adam, Alexander David, Di Pietrantonio Tania, Girard Manon, Jones Joses, Schurr Erwin, Liu Jun, Sherman David R, Behr Marcel A

Abstract excerpt

BCG vaccines are a family of closely related daughter strains of an attenuated isolate of Mycobacterium bovis derived by in vitro passage from 1908 to 1921. During subsequent laboratory propagation of the vaccine strain until its lyophilization in 1961, BCG Pasteur underwent at least seven further genomic mutations. The impact of these mutations on the properties of the vaccine is currently unknown. One mutation,...

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Identifiers

PMID: 15102790
DOI: 10.1128/IAI.72.5.2803-2809.2004
PMCID: PMC387861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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