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Article

Manipulation of BCG vaccine: a double-edged sword

25 Jan 2016

Abstract excerpt

Mycobacterium bovis Bacillus Calmette-Guérin (BCG), an attenuated vaccine derived from M. bovis, is the only licensed vaccine against tuberculosis (TB). Despite its protection against TB in children, the protective efficacy in pulmonary TB is variable in adolescents and adults. In spite of the current knowledge of molecular biology, immunology and cell biology, infectious diseases such as TB and HIV/AIDS are...

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PMID: 26810060
DOI: 10.1007/s10096-016-2579-y

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