Article
Residual chloride secretion in intestinal tissue of deltaF508 homozygous twins and siblings with cystic fibrosis. The European CF Twin and Sibling Study Consortium.
Gastroenterology - 1 Jul 2000
Bronsveld I, Mekus F, Bijman J, Ballmann M, Greipel J, Hundrieser J, Halley D J, Laabs U, Busche R, De Jonge H R, Tümmler B, Veeze H J
Abstract excerpt
BACKGROUND & AIMS: Cholinergic stimulation of chloride secretion is impaired in the intestines of patients with cystic fibrosis (CF). However, intestinal chloride secretion has been observed in patients with mild CF mutations. The aim of this study was to investigate residual Cl(-) secretion in the intestine of DeltaF508 homozygous CF patients, and examine the contribution of cystic fibrosis transmembrane...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.