Article
Conserved (CT)n.(GA)n repeats in the non-coding regions at the Gpdh locus are binding sites for the GAGA factor in drosophila melanogaster and its sibling species.
Genetica - 1 May 2004
Tchoubrieva E B, Gibson J B
Abstract excerpt
The (CT)n.(GA)n rich sequences in the upstream and 5' intron enhancer regions of the sn-glycerol-3-phosphate dehydrogenase (Gpdh) gene in Drosophila melanogaster, its sibling and distantly related species are conserved in their position and in the number of repeats. Using in vitro DNA-footprint analyses we show that the GAGA factor binds to these multiple closely spaced and overlapping conserved (CT)n.(GA)n...
Topics
- Alleles
- Animals
- Base Sequence
- Binding Sites
- Chromosome Mapping
- Conserved Sequence
- DNA-Binding Proteins
- Dinucleotide Repeats
- Drosophila
- Drosophila Proteins
- Drosophila melanogaster
- Introns
- Molecular Sequence Data
- Transcription Factors