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Article

Retrotransposon insertion induces an isozyme of sn-glycerol-3-phosphate dehydrogenase in Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 1995

Wilanowski T M, Gibson J B, Symonds J E

Abstract excerpt

The insertion of the blood retrotransposon into the untranslated region of exon 7 of the sn-glycerol-3-phosphate dehydrogenase-encoding gene (Gpdh) in Drosophila melanogaster induces a GPDH isozyme-GPDH-4-and alters the pattern of expression of the three normal isozymes-GPDH-1 to GPDH-3. The process of transcript terminus formation inside the retrotransposon insertion reduces the level of the Gpdh transcript that...

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PMID: 8618845
DOI: 10.1073/pnas.92.26.12065
PMCID: PMC40297

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