Article
Defective P element insertions affect the expression of sn-glycerol-3-phosphate dehydrogenase alleles in natural populations of Drosophila melanogaster.
Proceedings. Biological sciences - 22 Jan 1993
Reed D S, Gibson J B
Abstract excerpt
A distinctive and geographically widespread category of low-activity variant at the Gpdh locus in Drosophila melanogaster is shown to have defective P elements inserted between the TATA box and the transcription start site. In four examples the insertion was a single 1.15 kilobase (kb) KP element, whereas in another variant there were two KP elements in tandem. A sixth example contained a 0.61 kb defective P...
Topics
- Alleles
- Animals
- Base Sequence
- Cloning, Molecular
- DNA
- DNA Transposable Elements
- Drosophila melanogaster
- Gene Expression Regulation, Enzymologic
- Glycerolphosphate Dehydrogenase
- Mutagenesis, Insertional