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Article

Combined association and linkage analysis applied to the APOE locus.

Genetic epidemiology - 1 May 2004

Beekman Marian, Posthuma Daniëlle, Heijmans Bastiaan T, Lakenberg Nico, Suchiman H Eka D, Snieder Harold, de Knijff Peter, Frants Rune R, van Ommen Gert Jan B, Kluft Cornelis, Vogler George P, Slagboom P Eline, Boomsma Dorret I

Abstract excerpt

Combined association and linkage analysis is a powerful tool for pinpointing functional quantitative traits (QTLs) responsible for regions of significant linkage identified in genome-wide scans. We applied this technique to apoE plasma levels and the APOEepsilon2/epsilon3/epsilon4 polymorphism in...

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Source

Identifiers

PMID: 15095392
DOI: 10.1002/gepi.10318

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15095392-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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