Article
Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak.
Genetic epidemiology - 1 Feb 2006
Larkin Emma K, Patel Sanjay R, Redline Susan, Mignot Emmanuel, Elston Robert C, Hallmayer Joachim
Abstract excerpt
Evidence from both linkage analyses and association-based analyses has implicated Apoliprotein E (ApoE) as a disease susceptibility locus for obstructive sleep apnea. To further assess the putative role of ApoE in sleep apnea, we performed genotyping, association, and linkage analyses in a cohort assembled to investigate the genetic epidemiology of sleep apnea. Among a subset of the Caucasian families, ten...
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