Article
Inactivating mutation of the pro-apoptotic gene BID in gastric cancer.
The Journal of pathology - 1 Apr 2004
Lee Jong Heun, Soung Young Hwa, Lee Jong Woo, Park Won Sang, Kim Su Young, Cho Yong Gu, Kim Chang Jae, Seo Si Hyung, Kim Hong Sug, Nam Suk Woo, Yoo Nam Jin, Lee Sug Hyung, Lee Jung Young
Abstract excerpt
There is evidence that deregulation of apoptosis is mechanistically involved in cancer development and somatic mutations of apoptosis-related genes have been reported in human cancers. BID, a pro-apoptotic member of the Bcl-2 family, interconnects the extrinsic apoptosis pathway initiated by deat...
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