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Article

Enhanced long-term potentiation in vivo in dentate gyrus of NELL2-deficient mice.

Neuroreport - 1 Mar 2004

Matsuyama Shogo, Aihara Koutoku, Nishino Naoki, Takeda Satoshi, Tanizawa Katsuyuki, Kuroda Shun'ichi, Horie Masato

Abstract excerpt

NELL2 is a neuron-specific thrombospondin-1-like extracellular protein containing six epidermal growth factor-like domains and is highly expressed in the hippocampus. We have previously shown that NELL2 promotes survival of neurons through mitogen-activated protein kinases. To clarify the function of NELL2 in vivo, we have generated a novel strain of mice with a targeted mutation in the NELL2 gene and assessed...

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Source

Identifiers

PMID: 15094495
DOI: 10.1097/00001756-200403010-00007

Genes

NELL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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