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Article

Pumilio-2 function in the mouse nervous system.

PloS one - 1 Jan 2011

Siemen Henrike, Colas Damien, Heller H Craig, Brüstle Oliver, Pera Renee A Reijo

Abstract excerpt

Coordinated mRNA translation at the synapse is increasingly recognized as a critical mechanism for neuronal regulation. Pumilio, a translational regulator, is known to be involved in neuronal homeostasis and memory formation in Drosophila. Most recently, the mammalian Pumilio homolog Pumilio-2 (Pum2) has been found to play a role in the mammalian nervous system, in particular in regulating morphology,...

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Identifiers

PMID: 22016787
DOI: 10.1371/journal.pone.0025932
PMCID: PMC3189250

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