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Article

Differentiation phenotypes of pancreatic islet beta- and alpha-cells are closely related with homeotic genes and a group of differentially expressed genes.

Gene - 28 Apr 2004

Mizusawa Noriko, Hasegawa Tomoko, Ohigashi Izumi, Tanaka-Kosugi Chisato, Harada Nagakatsu, Itakura Mitsuo, Yoshimoto Katsuhiko

Abstract excerpt

To identify the genes that determine differentiation phenotypes, we compared gene expression of pancreatic islet beta- and alpha-cells, which are derived from the common precursor and secrete insulin and glucagon, respectively. The expression levels of homeotic genes including Hox genes known to determine region specificity in the antero-posterior (AP) body axis, tissue-specific homeobox genes, and other 8,734...

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Identifiers

PMID: 15094191
DOI: 10.1016/j.gene.2004.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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