Article
Coronary artery disease and the thrombospondin single nucleotide polymorphisms.
The international journal of biochemistry & cell biology - 1 Jun 2004
Stenina Olga I, Byzova Tatiana V, Adams Josephine C, McCarthy Jeanette J, Topol Eric J, Plow Edward F
Abstract excerpt
GeneQuest was a high throughput, large-scale analysis of single nucleotide polymorphisms (SNPs) to identify gene associated with familial, premature coronary artery disease and myocardial infarction. The three SNPs showing the highest and most significant associations with disease were all members of the thrombospondin gene family, thrombospondin-1, thrombospondin-2 and thrombospondin-4. These unanticipated...
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