Article
The 4G/5G polymorphism of the plasminogen activator inhibitor gene is associated with the time course of progression to acute coronary syndromes.
Atherosclerosis - 1 Jan 1998
Iwai N, Shimoike H, Nakamura Y, Tamaki S, Kinoshita M
Abstract excerpt
The 4G allele of the plasminogen activator inhibitor (PAI-I) gene is associated with increased PAI-I levels. Increased PAI-I levels have been reported to be associated with atherothrombotic events. However, the significance of the 4G/5G polymorphism of the PAI-I gene in the pathogenesis of ischemic heart diseases has not been determined. We assessed the 4G/5G polymorphism of the PAI-I gene in 500 subjects...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.