Article
Intronic sequence with both negative and positive effects on the regulation of alternative transcripts of the chicken beta tropomyosin transcripts.
Nucleic acids research - 11 Aug 1992
Balvay L, Libri D, Gallego M, Fiszman M Y
Abstract excerpt
The chicken beta tropomyosin gene generates three major transcripts by alternative splicing. A pair of internal exons are spliced in a mutually exclusive manner and their utilisation is developmentally regulated. Exon 6A and exon 6B are used respectively in myoblasts and myotubes during the process of differentiation of muscle cells. We have previously reported that, in myoblasts, exon 6B is skipped because of a...
Topics
- Animals
- Base Sequence
- Cell Line, Transformed
- Chickens
- Exons
- Introns
- Molecular Sequence Data
- Mutation
- Plasmids
- Polymerase Chain Reaction
- RNA Splicing