Identification and Expression Profile of a Novel Alternative Splicing of Pax7 in Chick Skeletal Muscle

Abstract excerpt

Pax7 is essential for skeletal muscle myogenesis. The alternative splicing forms of Pax7 were found in human and mouse. In this study, we identified a new alternative splicing of chick Pax7. We named it Pax7-2 and localized it in the nucleus of chick myoblast. In Pax7-2 mRNA, exon 8 of chick Pax7 gene was spliced out. That led to a 22-amino acid deletion in the COOH terminal of Pax7-2 protein compared with Pax7...

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