Article
Alternative splicing of Xenopus alphafast-tropomyosin pre-mRNA during development: identification of determining sequences.
DNA and cell biology - 1 Jun 2000
Duriez P, Lesimple M, Allo M R, Hardy S
Abstract excerpt
The Xenopus alphafast-tropomyosin gene contains in its central part a set of mutually exclusive exons, designated 6A and 6B, which are incorporated into mRNA encoding, respectively, nonmuscle and muscle tropomyosins. In this study, we show that usage of both exons is strictly regulated during development, exon 6A being used in the oocyte and nonmuscle tissues of the embryo, while exon 6B is used in muscle...
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