Article
Association between glutathione-S-transferase GSTP1 genotypes, GSTP1 over-expression, and outcome in epithelial ovarian cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000
Howells R E J, Dhar K K, Hoban P R, Jones P W, Fryer A A, Redman C W E, Strange R C
Abstract excerpt
Ovarian cancer accounts for the majority of deaths from gynaecological malignancy, and polymorphisms in genes encoding the glutathione-S-transferase (GST) GSTP1 detoxifying enzymes may lead to variation in detoxification of carcinogens. We describe a study involving 81 women with invasive epithelial ovarian cancer. A number of important clinical variables and outcome data were obtained. GSTP1 genotyping was...
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