Article
Association of GSTP1 methylation with aggressive phenotype in ER-positive breast cancer.
Anticancer research - 1 Dec 2013
Miyake Tomohiro, Nakayama Takahiro, Kagara Naofumi, Yamamoto Noriaki, Nakamura Yukiko, Otani Yoko, Uji Kumiko, Naoi Yasuto, Shimoda Masafumi, Maruyama Naomi, Shimomura Atsushi, Shimazu Kenzo, Kim Seung Jin, Noguchi Shinzaburo
Abstract excerpt
AIM: We investigated the association of glutathione S-transferase P1 (GSTP1) expression and methylation status with clinicopathological characteristics of estrogen receptor (ER)-positive breast cancers. MATERIALS AND METHODS: Primary ER-positive breast cancer patients (n=177, stage I-III) were retrospectively analyzed. A quantitative GSTP1 methylation assay was performed using DNA micro-dissected from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
