Article
Polymorphic expression of glutathione transferases A1, M1, P1 and T1 in epithelial ovarian cancer: a Serbian case-control study.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Pljesa Igor, Berisavac Milica, Simic Tatjana, Pekmezovic Tatjana, Coric Vesna, Suvakov Sonja, Stamatovic Ljiljana, Matic Marija, Gutic Bojana, Milenkovic Sanja, Pljesa-Ercegovac Marija, Savic-Radojevic Ana
Abstract excerpt
PURPOSE: Since several studies have proposed that epithelial ovarian cancer should not be considered as a single disease entity and that it results from an accumulation of genetic changes, we aimed to assess the polymorphic expression of major cytosolic glutathione S-transferases (GSTM1, T1, A1 and P1) with respect to ovarian cancer susceptibility and aggressiveness. METHODS: This case-control study was conducted...
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