Article
Cytokine gene polymorphisms in hemodialysis patients: association with comorbidity, functionality, and serum albumin.
Kidney international - 1 Apr 2004
Balakrishnan Vaidyanathapuram S, Guo Daqing, Rao Madhumathi, Jaber Bertrand L, Tighiouart Hocine, Freeman Richard L, Huang Chao, King Andrew J, Pereira Brian J G
Abstract excerpt
BACKGROUND: Cytokine-orchestrated chronic inflammation plays a major role in long-term morbidity and mortality in patients with end-stage renal disease (ESRD) on hemodialysis (HD). In this cross-sectional study, we evaluated the association between specific alleles/genotypes and combinations of genotypes of interleukin (IL)-6, tumor necrosis factor-alpha (TNF-alpha), and IL-10 with indices of comorbidity,...
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