Article
T-cell receptor BV gene segment polymorphisms in healthy elderly individuals from the south of Brazil.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 2004
Peres A, Hünemeier T, Da Cruz I M, Nardi N B, Chies J A B
Abstract excerpt
The ageing of the immune system (immunosenescence) is believed to be involved in both morbidity and mortality in elderly humans due to a higher incidence of infections, autoimmune diseases, cancers and other pathological situations. As any specific immune response involves recognition of antigens by T cells, the ability to develop a given immune response is also dependent on the T-cell repertoire available at a...
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