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Article

Single nucleotide polymorphism characterization by mRNA expression imbalance assessment.

Pharmacogenetics - 1 Apr 2004

Wojnowski Leszek, Brockmöller Jürgen

Abstract excerpt

The functional characterization of single nucleotide polymorphism (SNPs) represents a major challenge for pharmacogenetics and related research areas. Here, we propose a procedure, termed mRNA expression imbalance assessment, that can be applied to detect cis-acting SNPs with an effect on mRNA expression. The procedure is based on the observation that the relative transcript levels derived from the two alleles of...

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PMID: 15083072
DOI: 10.1097/00008571-200404000-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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