Article
NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.
Biochemical and biophysical research communications - 15 Jul 2005
Hunter Michael, Angelicheva Dora, Tournev Ivailo, Ingley Evan, Chan Dick C, Watts Gerald F, Kremensky Ivo, Kalaydjieva Luba
Abstract excerpt
Hereditary Motor and Sensory Neuropathy Lom (HMSNL) is a severe autosomal recessive peripheral neuropathy, the most common form of demyelinating Charcot-Marie-Tooth (CMT) disease in the Roma (Gypsy) population. The mutated gene, N-myc downstream-regulated gene 1 (NDRG1), is widely expressed and has been implicated in a range of processes and pathways. To gain an insight into NDRG1 function we performed yeast...
Topics
- Animals
- Apolipoprotein A-I
- Apolipoprotein A-II
- COS Cells
- Cell Cycle Proteins
- Cell Line
- Charcot-Marie-Tooth Disease
- Cholesterol
- Cholesterol, HDL
- Chromosomes, Human, Pair 8
