Article
Insertion of the beta Geo promoter trap into the Fem1c gene of ROSA3 mice.
Molecular and cellular biology - 1 May 2004
Schlamp Cassandra L, Thliveris Andrew T, Li Yan, Kohl Louis P, Knop Claudia, Dietz Joel A, Larsen Inna V, Imesch Pascal, Pinto Lawrence H, Nickells Robert W
Abstract excerpt
ROSA3 mice were developed by retroviral insertion of the beta Geo gene trap vector. Adult ROSA3 mice exhibit widespread expression of the trap gene in epithelial cells found in most organs. In the central nervous system the highest expression of beta Geo is found in CA1 pyramidal cells of the hippocampus, Purkinje cells of the cerebellum, and ganglion cells of the retina. Characterization of the genomic insertion...
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