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Article

Stress response induced by DNA damage leads to specific, delayed and untargeted mutations.

Molecular & general genetics : MGG - 1 Aug 1992

Boesen J J, Stuivenberg S, Thyssens C H, Panneman H, Darroudi F, Lohman P H, Simons J W

Abstract excerpt

Cells of the mouse T-lymphoma line GRSL13 were treated with 8-methoxy-psoralen plus longwave ultraviolet light (PUVA) under conditions where the biological effects are mainly due to non-persistent DNA cross-links (PUVA-CL treatment). Fluctuation analysis showed that PUVA-CL treatment resulted in an enhancement of the mutation rate in the progeny of treated cells, which persisted until the eleventh generation...

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Identifiers

PMID: 1508148
DOI: 10.1007/BF00283842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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