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Article

Radiation induced dynamic mutations and transgenerational effects.

Journal of radiation research - 1 Jan 2006

Niwa Ohtsura

Abstract excerpt

Many studies have confirmed that radiation can induce genomic instability in whole body systems. Although the molecular mechanisms underlying induced genomic instability are not known at present, this interesting phenomenon could be the manifestation of a cellular fail-safe system in which fidelity of repair and replication is down-regulated to tolerate DNA damage. Two features of genomic instability namely,...

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PMID: 17019049
DOI: 10.1269/jrr.47.b25

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