Article
Acetylator polymorphism in multiple sclerosis.
Acta neurologica Scandinavica - 1 Feb 1994
Ladero J M, Arroyo R, De Andrés C, Jiménez-Jiménez F J, Molina J A, Varela de Seijas E, Giménez-Roldán S, Benítez J
Abstract excerpt
To elucidate whether any relationship exists between genetic polymorphic acetylation and the risk for multiple sclerosis (MS), we determined this polymorphism, using sulphamethazine, in 71 patients with definite MS and in 268 age-matched controls. Thirty-seven patients (52.1%) and 151 controls (56.3%) were classified as slow acetylators (not significant difference). No relation was found between acetylator...
Topics
- Acetylation
- Adult
- Female
- Humans
- Male
- Multiple Sclerosis
- Phenotype
- Polymorphism, Genetic
- Risk Factors
- Sulfamethazine