Article
Functional polymorphisms in LPS receptors CD14 and TLR4 are not associated with disease susceptibility or Campylobacter jejuni infection in Guillain-Barré patients.
Journal of neuroimmunology - 1 May 2004
Geleijns Karin, Jacobs Bart C, Van Rijs Wouter, Tio-Gillen Anne P, Laman Jon D, van Doorn Pieter A
Abstract excerpt
Guillain-Barré syndrome (GBS) is an acute immune-mediated polyneuropathy preceded by infections. Campylobacter jejuni is the most frequent pathogen and its lipopolysaccharide (LPS) induces antibodies cross-reactive with gangliosides. In this study we assessed whether known functional polymorphisms in the LPS receptors CD14 and Toll-like receptor 4 (TLR4) are associated with an increased susceptibility for GBS or...
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