Article
Distinct DNA methylation profiles in ovarian serous neoplasms and their implications in ovarian carcinogenesis.
American journal of obstetrics and gynecology - 1 Dec 2010
Shih Ie-Ming, Chen Li, Wang Chen C, Gu Jinghua, Davidson Ben, Cope Leslie, Kurman Robert J, Xuan Jianhua, Wang Tian-Li
Abstract excerpt
OBJECTIVE: The purpose of this study was to analyze DNA methylation profiles among different types of ovarian serous neoplasm, which is a task that has not been performed. STUDY DESIGN: The Illumina beads array (Illumina Inc, San Diego, CA) was used to profile DNA methylation in enriched tumor cells that had been isolated from 75 benign and malignant serous tumor tissues and 6 tumor-associated stromal cell...
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