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Article

Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch.

Pharmacogenetics - 1 Feb 2004

Johnstone Elaine C, Yudkin Patricia L, Hey Kate, Roberts Sarah J, Welch Sarah J, Murphy Michael F, Griffiths Siân E, Walton Robert T

Abstract excerpt

Polymorphisms in the dopamine D2 receptor (DRD2 C/T and DRD2 A/G) and in dopamine beta hydroxylase (DBH A/G) have been implicated in modulation of smoking and other reward-seeking behaviours. We hypothesized that these alleles would predict the outcome of nicotine patch therapy for smoking cessat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15077009
DOI: 10.1097/00008571-200402000-00002

Genes

DRD2
DBH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15077009-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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