Article
C18orf1 located on chromosome 18p11.2 may confer susceptibility to schizophrenia.
Journal of medical and dental sciences - 1 Sept 2003
Kikuchi Mika, Yamada Kazuo, Toyota Tomoko, Yoshikawa Takeo
Abstract excerpt
The pericentromeric region of chromosome 18, especially 18p11.2, is described as a schizophrenia susceptibility locus. We had previously cloned two novel brain-derived transcripts from this region: the gene for a second human myo-inositol monophosphatase (IMPA2) and a gene of unknown function, C18orf1. Recently, we reported a distortion of transmission of the tandem repeat marker D18S852, embedded in the...
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