Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An analysis of tumor necrosis factor alpha gene polymorphisms and haplotypes with natural clearance of hepatitis C virus infection.

Genes and immunity - 1 Jun 2004

Thio C L, Goedert J J, Mosbruger T, Vlahov D, Strathdee S A, O'Brien S J, Astemborski J, Thomas D L

Abstract excerpt

The cytokine tumor necrosis factor alpha (TNF-alpha) is important in generating an immune response against a hepatitis C virus (HCV) infection. The functions of TNF-alpha may be altered by single-nucleotide polymorphisms (SNPs) in its gene, TNF. We hypothesized that SNPs in TNF may be important in determining the outcome of an HCV infection. To test this hypothesis, we typed nine TNF SNPs in a cohort of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to TNF gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Hepacivirus

Share to Hepatitis C

Share to Polymorphism, Single Nucleotide

Share to Tumor Necrosis Factor-alpha

Share to White People

Source

Identifiers

PMID: 15071492
DOI: 10.1038/sj.gene.6364072

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An analysis of tumor necrosis factor alpha gene polymorphisms and haplotypes with natural clearance of hepatitis C virus infection.PMID 15071492Read ↗

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.Semantic proximity Read ↗

Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection.Semantic proximity Read ↗

Relationship between TNF-<alpha> gene promoter polymorphisms and outcomes of hepatitis B virus infections: a meta-analysis.Semantic proximity Read ↗

Association of TNF-beta polymorphism with disease severity among patients infected with hepatitis C virus.Semantic proximity Read ↗

Tumor necrosis factor gene polymorphisms and clearance or progression of hepatitis B virus infection.Semantic proximity Read ↗

Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection.Semantic proximity Read ↗

Single nucleotide polymorphisms and haplotypes in the IL10 region associated with HCV clearance.Semantic proximity Read ↗

A tumor necrosis factor-alpha (TNF-alpha) promoter polymorphism is associated with chronic hepatitis B infection.Semantic proximity Read ↗

Genetic Variation on TNF/LTA and TNFRSF1A Genes is Associated with Outcomes of Hepatitis C Virus Infection.Semantic proximity Read ↗

IL-10 and TNF-alpha polymorphisms and the recovery from HCV infection.Semantic proximity Read ↗

Tumor Necrosis Factor-Alpha Gene Polymorphism Associated With Development of Hepatitis B Virus-associated Hepatocellular Carcinoma.Semantic proximity Read ↗

Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.