Article
An analysis of tumor necrosis factor alpha gene polymorphisms and haplotypes with natural clearance of hepatitis C virus infection.
Genes and immunity - 1 Jun 2004
Thio C L, Goedert J J, Mosbruger T, Vlahov D, Strathdee S A, O'Brien S J, Astemborski J, Thomas D L
Abstract excerpt
The cytokine tumor necrosis factor alpha (TNF-alpha) is important in generating an immune response against a hepatitis C virus (HCV) infection. The functions of TNF-alpha may be altered by single-nucleotide polymorphisms (SNPs) in its gene, TNF. We hypothesized that SNPs in TNF may be important i...
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