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Article

Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype.

Leukemia & lymphoma - 1 Aug 2012

Shimura Hanae, Mori Naoki, Wang Yan-Hua, Okada Michiko, Motoji Toshiko

Abstract excerpt

Retinoblastoma protein-interacting zinc finger, RIZ1, is a tumor suppressor gene that is inactivated in various solid tumors. However, the role of the RIZ1 gene has not been well examined in adult acute lymphoblastic leukemia (ALL). We analyzed the expression and promoter methylation status of the RIZ1 gene in patients with newly diagnosed ALL by quantitative real-time reverse transcription polymerase chain...

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Share to Cell Cycle
Share to Cytogenetics
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

Share to Polymorphism, Single-Stranded Conformational

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Real-Time Polymerase Chain Reaction

Share to T-Lymphocytes

Source

Identifiers

PMID: 22300346
DOI: 10.3109/10428194.2012.663086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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