Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low docosahexaenoic acid levels in rod outer segments of rats with P23H and S334ter rhodopsin mutations.

Molecular vision - 23 Sept 2002

Anderson Robert E, Maude Maureen B, McClellan Mark, Matthes Michael T, Yasumura Douglas, LaVail Matthew M

Abstract excerpt

PURPOSE: Previous studies have shown that the level of docosahexaenoic acid (22:6n-3, DHA) is lower in the rod outer segment (ROS) membranes of dogs and mice with inherited retinal degeneration than in ROS from appropriate controls. In the present study, we analyzed the ROS fatty composition of several lines of transgenic rats with P23H and S334ter rhodopsin mutations. Lines were chosen that have different rates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Chromatography, Gas

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Docosahexaenoic Acids

Share to Electrophoresis, Polyacrylamide Gel

Share to Rats, Sprague-Dawley

Share to Retinal Degeneration

Share to Rhodopsin

Share to Rod Cell Outer Segment

Source

Identifiers

PMID: 12355064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low docosahexaenoic acid levels in rod outer segments of rats with P23H and S334ter rhodopsin mutations.PMID 12355064Read ↗

Lipid differences in rod outer segment membranes of rats with P23H and S334ter opsin mutations.Semantic proximity Read ↗

P23H and S334ter opsin mutations: Increasing photoreceptor outer segment n-3 fatty acid content does not affect the course of retinal degeneration.Semantic proximity Read ↗

Low docosahexaenoic acid levels in rod outer segment membranes of mice with rds/peripherin and P216L peripherin mutations.Semantic proximity Read ↗

A hypothesis to explain the reduced blood levels of docosahexaenoic acid in inherited retinal degenerations caused by mutations in genes encoding retina-specific proteins.Semantic proximity Read ↗

High levels of retinal docosahexaenoic acid do not protect photoreceptor degeneration in VPP transgenic mice.Semantic proximity Read ↗

Retinal cAMP levels during the progression of retinal degeneration in rhodopsin P23H and S334ter transgenic rats.Semantic proximity Read ↗

Effect of visible light on normal and P23H-3 transgenic rat retinas: characterization of a novel retinoic acid derivative present in the P23H-3 retina.Semantic proximity Read ↗

Retinoid kinetics in eye tissues of VPP transgenic mice and their normal littermates.Semantic proximity Read ↗

Susceptibility to retinal light damage in transgenic rats with rhodopsin mutations.Semantic proximity Read ↗

Retinal metabolic state of the proline-23-histidine rat model of retinitis pigmentosa.Semantic proximity Read ↗

Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration.Semantic proximity Read ↗

Docosahexaenoic acid phospholipid differentially modulates the conformation of G90V and N55K rhodopsin mutants associated with retinitis pigmentosa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.