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Article

A functional variant of IRS1 is associated with type 1 diabetes in families from the US and UK.

Molecular genetics and metabolism - 1 Apr 2004

Morrison V Anne, Onengut-Gumuscu Suna, Concannon Patrick

Abstract excerpt

A collection of 767 multiplex type 1 diabetes families from the US and UK were tested for linkage to the IRS1 gene and for allelic association with a specific variant of IRS1, G972R. Pedigree disequilibrium testing revealed preferential transmission of the 972R allele to affected offspring in the...

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Source

Identifiers

PMID: 15059616
DOI: 10.1016/j.ymgme.2003.10.018

Genes

IRS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15059616-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A functional variant of IRS1 is associated with type 1 diabetes in families from the US and UK.PMID 15059616Read ↗

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