Article
Identification of candidate genes involved in the reversal of malignant phenotype of osteosarcoma cells transfected with the liver/bone/kidney alkaline phosphatase gene.
Bone - 1 Apr 2004
Zucchini Cinzia, Bianchini Michele, Valvassori Luisa, Perdichizzi Stefania, Benini Stefania, Manara Maria Cristina, Solmi Rossella, Strippoli Pierluigi, Picci Piero, Carinci Paolo, Scotlandi Katia
Abstract excerpt
Alkaline phosphatases (ALPs) are a family of cell surface glycoproteins that catalyze the hydrolysis of phosphomonoesters with release of inorganic phosphate. Liver/bone/kidney (L/B/K) ALP participates in bone mineralization, but its other physiological and pathological functions remain obscure....
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