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Article

Haptoglobin phenotypes differ in their ability to inhibit heme transfer from hemoglobin to LDL.

Biochemistry - 6 Apr 2004

Bamm Vladimir V, Tsemakhovich Vladimir A, Shaklai Matityahu, Shaklai Nurith

Abstract excerpt

LDL oxidation plays a pivotal role in atherosclerosis. Excellular hemoglobin (Hb) is a trigger of LDL oxidation. By virtue of its ability to bind hemoglobin, haptoglobin (Hp) serves as an antioxidant. Oxidation of LDL by hemoglobin was analyzed to occur by heme displacement from methemoglobin lod...

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Identifiers

PMID: 15049697
DOI: 10.1021/bi0362626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15049697-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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