Article
Influence of human haptoglobin polymorphism on oxidative stress induced by free hemoglobin on red blood cells.
Clinical chemistry and laboratory medicine - 1 Jan 2006
Guéye Papa Madièye, Glasser Nicole, Férard Georges, Lessinger Jean-Marc
Abstract excerpt
BACKGROUND: An in vitro study was conducted to determine whether haptoglobin phenotypes differed in their protective effect against oxidative stress induced by extracellular hemoglobin on red blood cells. METHODS: Conjugated dienes and thiobarbituric acid-reactive substances (TBARS) were determined in human red blood cell membranes in the presence of hemoglobin and various concentrations of each type of purified...
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