Article
The role of Toll-like receptor 4 versus interleukin-12 in immunity to respiratory syncytial virus.
European journal of immunology - 1 Apr 2004
Ehl Stephan, Bischoff Ruth, Ostler Tobias, Vallbracht Simone, Schulte-Mönting Jürgen, Poltorak Alexander, Freudenberg Marina
Abstract excerpt
Toll-like receptors (TLR) and IL-12 represent key elements of innate immunity. Using C57BL/10 ScCr mice it was shown that TLR4 is important for control of infection with respiratory syncytial virus (RSV). Since these mice have an additional defect in the IL-12R, we reinvestigated immunity to RSV...
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