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Article

Induction of autoantibodies to CCR5 in macaques and subsequent effects upon challenge with an R5-tropic simian/human immunodeficiency virus.

Journal of virology - 1 Apr 2004

Chackerian Bryce, Briglio Lindsey, Albert Paul S, Lowy Douglas R, Schiller John T

Abstract excerpt

Antibodies against CCR5, the major coreceptor for human immunodeficiency virus type 1 (HIV-1), may have antiviral potential as viral fusion inhibitors. In this study, we generated a virus-like particle (VLP)-based vaccine that effectively breaks B-cell tolerance and elicits autoantibodies against...

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Share to AIDS Vaccines
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin G

Share to Macaca nemestrina

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Source

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Identifiers

PMID: 15047820
DOI: 10.1128/jvi.78.8.4037-4047.2004
PMCID: PMC374281

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15047820-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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