Article
Molecular mechanisms of MHC linked susceptibility in leprosy: towards the development of synthetic vaccines.
Tuberculosis (Edinburgh, Scotland) - 1 Jan 2004
Gorodezky Clara, Alaez Carmen, Munguía Andrea, Cruz Rocío, Vazquez Alejandra, Camacho Alejandra, Flores Oscar, Rodriguez Mirna, Rodriguez Obdulia
Abstract excerpt
Tuberculoid (TT) and lepromatous leprosy (LL) develop in the human host depending on his ability to trigger a specific cellular immune response(CIR). Different genes have been demonstrated in susceptibility/protection and may explain the forms of leprosy. The major histocompatibility complex (MHC) play an important role. The aim of the study was to explore the contribution of human leukocyte antigen (HLA) DRB1,...
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